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Carissimo Annamaria

Short Biography

Education
  • 2002 “Laurea cum laude” Degree in Mathematics at Second University of Naples.
  • 2007 Ph.D. in Environmental Engineering at University of Basilicata.
Technical Skills
  • Statistical Analysis
  • Microarray Data Analysis
  • Design of Experiments
Publications
  • Piccolo P, Annunziata P, Soria LR, Attanasio S, Barbato A, Castello R, Carissimo A, Quagliata L, Terracciano LM, Brunetti-Pierri N. Downregulation of HNF-4α and defective zonation in livers expressing mutant Z α1-antitrypsin. Hepatology. 2017 Mar 15. doi: 10.1002/hep.29160.
  • Dell'Aversana C, Giorgio C, D'Amato L, Lania G, Matarese F, Saeed S, Di Costanzo A, Belsito Petrizzi V, Ingenito C, Martens JH, Pallavicini I, Minucci S, Carissimo A, Stunnenberg HG, Altucci L. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2017 Mar 10. doi: 10.1038/leu.2017.64
  • Gambardella G, Carissimo A, Chen A, Cutillo L, Nowakowski TJ, di Bernardo D, Blelloch R. The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells. Nat Commun. 2017 Jan 19;8:14126. doi: 10.1038/ncomms14126.
  • Concilli M, Iacobacci S, Chesi G, Carissimo A, Polishchuk R. A systems biology approach reveals new endoplasmic reticulum-associated targets for the correction of the ATP7B mutant causing Wilson disease. Metallomics. 2016 Sep 1;8(9):920-930.
  • De Leo G. Staiano L, Vicinanza M, Luciani A, Carissimo A, Mutarelli M, Di Campli A, Polishchuk E, Di Tullio G, Morra V, Levtchenko E, Oltrabella F, Starborg T, Santoro M, di Bernardo D, Devuyst O, Lowe M, Medina DL, Ballabio A, De Matteis MA, Autophagosome–lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL. Nat Cell Biol. 2016 Aug;18(8):839-50. doi: 10.1038/ncb3386. Epub 2016 Jul 11
  • Pinelli M, Carissimo A, Cutillo L, Lai CH, Mutarelli M, Moretti MN, Singh MV, Karali M, Carrella D, Pizzo M, Russo F, Ferrari S, Ponzin D, Angelini C, Banfi S, di Bernardo D. An atlas of gene expression and gene co-regulation in the human retina. Nucleic Acids Res. 2016 May 27. doi: 10.1093/nar/gkw486
  • Botta S, Marrocco E, de Prisco N, Curion F, Renda M, Sofia M, Lupo M, Carissimo A, Bacci ML, Gesualdo C, Rossi S, Simonelli F, Surace EM: Rhodopsin targeted transcriptional silencing by DNA-binding. Elife. 2016 Mar 14;5. pii: e12242. doi: 10.7554/eLife.12242.
  • Karali M, Persico M, Mutarelli M, Carissimo A, Pizzo M, Singh Marwah V, Ambrosio C, Pinelli M, Carrella D, Ferrari S, Ponzin D, Nigro V, di Bernardo D, Banfi S. High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs. Nucleic Acids Res. 2016 Feb 29;44(4):1525-40. doi: 10.1093/nar/gkw039. Epub 2016 Jan 26.
  • Hegde RN, Parashuraman S, Iorio F, Ciciriello F, Capuani F, Carissimo A, Carrella D, Belcastro V, Subramanian A, Bounti L, Persico M, Carlile G, Galietta L, Thomas DY, Di Bernardo D, Luini A. Unravelling druggable signalling networks that control F508del-CFTR proteostasis. Elife. 2015 Dec 23;4. pii: e10365. doi: 10.7554/eLife.10365.
  • Chesi G, Hegde RN, Iacobacci S, Concilli M, Parashuraman S, Festa BP, Polishchuk EV, Di Tullio G, Carissimo A, Montefusco S, Canetti D, Monti M, Amoresano A, Pucci P, van de Sluis B, Lutsenko S, Luini A, Polishchuk RS. Identification of p38 MAPK and JNK as new targets for correction of Wilson disease-causing ATP7B mutants. Hepatology. 2015 Dec 13. doi: 10.1002/hep.28398
  • Tebbi A, Levillayer F, Jouvion G, Fiette L, Soubigou G, Varet H, Boudjadja N, Cairo S, Hashimoto K, Suzuki AM, Carninci P, Carissimo A, di Bernardo D, Wei Y. Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress. Carcinogenesis. 2016 Jan;37(1):39-48. doi: 10.1093/carcin/bgv156. Epub 2015 Nov 5.
  • Calligaris R, Banica M, Roncaglia P, Robotti E, Finaurini S, Vlachouli C, Antonutti L, Iorio F, Carissimo A, Cattaruzza T, Ceiner A, Lazarevic D, Cucca A, Pangher N, Marengo E, di Bernardo D, Pizzolato G, Gustincich S. Blood transcriptomics of drug-naïve sporadic Parkinson's disease patients. BMC Genomics. 2015 Oct 28;16(1):876. doi: 10.1186/s12864
  • Conte I, Hadfield KD, Barbato S, Carrella S, Pizzo M, Bhat RS, Carissimo A, Karali M, Porter LF, Urquhart J, Hateley S, O'Sullivan J, Manson FD, Neuhauss SC, Banfi S, Black GC. MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma. Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3236-45. doi: 10.1073/pnas.1401464112. Epub 2015 Jun 8.
  • Caiazzo M, Giannelli S, Valente P, Lignani G, Carissimo A, Sessa A, Colasante G, Bartolomeo R, Massimino L, Ferroni S, Settembre C, Benfenati F, Broccoli V. Direct conversion of fibroblasts into functional astrocytes by defined transcription factors. Stem Cell Reports. 2015 Jan 13;4(1):25-36. doi: 10.1016/j.stemcr.2014.12.002. Epub 2014 Dec 31
  • D'Amato L, Dell'Aversana C, Conte M, Ciotta A, Scisciola L, Carissimo A, Nebbioso A, Altucci L. ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias. Epigenetics. 2015;10(1):6-18. doi: 10.4161/15592294.2014.988035. Epub 2015 Jan 27.
  • Conte M, Dell'Aversana C, Benedetti R, Petraglia F, Carissimo A, Petrizzi VB, D'Arco AM, Abbondanza C, Nebbioso A, Altucci L. HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape. Oncotarget. 2015 Jan 20;6(2):886-901
  • Carrella, D Napolitano, F Rispoli, R. Miglietta, M Carissimo, A Cutillo, L Sirci, F Gregoretti, F Di Bernardo, D. Mantra 2.0: an online collaborative resource for drug mode of action and repurposing by network analysis. Bioinformatics first published online February 20, (2014) doi:10.1093/bioinformatics/btu058
  • Settembre C, De Cegli R, Mansueto G, Saha PK, Vetrini F, Visvikis O, Huynh T, Carissimo A, Palmer D, Klisch TJ, Wollenberg AC, Di Bernardo D, Chan L, Irazoqui JE, Ballabio A. TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop. Nat Cell Biol. 2013 Jun;15(6):647-58. doi: 10.1038/ncb2718. Epub 2013 Apr 21. Erratum in: Nat Cell Biol. 2013 Aug;15(8):1016.
  • Miceli M, Franci G, Dell'Aversana C, Ricciardiello F, Petraglia F, Carissimo A, Perone L, Maruotti GM, Savarese M, Martinelli P, Cancemi M, Altucci L. MePR: a novel human mesenchymal progenitor model with characteristics of pluripotency. Stem Cells Dev. 2013 Sep 1;22(17):2368-83. doi: 10.1089/scd.2012.0498. Epub 2013 May 24.
  • Zhang D, Ciciriello F, Anjos SM, Carissimo A, Liao J, Carlile GW, Balghi H, Robert R, Luini A, Hanrahan JW, Thomas DY. Ouabain Mimics Low Temperature Rescue of F508del-CFTR in Cystic Fibrosis Epithelial Cells. Front Pharmacol. 2012 Oct 4;3:176. doi: 10.3389/fphar.2012.00176. eCollection 2012.
  • Cutillo L, Carissimo A, Figini S. Network selection: a method for ranked lists selection. PLoS One. 2012;7(8):e43678. doi: 10.1371/journal.pone.0043678. Epub 2012 Aug 24.
  • Masiello G., Serio C, Carissimo A, Grieco G (2009). Application of φ-IASI to IASI: retrieval products evaluation and radiative transfer consistency. ATMOSPHERIC CHEMISTRY AND PHYSICS, vol. 9; p.8771-8783. ISSN: 1680-7316, Published: 19 November 2009
  • C. Serio, G. Masiello, G. Greco, A. Carissimo, P. Di Girolamo, D. Summa, A. Rodriguez, R. Stuhlmann, S. Tjemkes Potential of MTG-IRS mission to resolve small scale variability of atmospheric humidity. AIP conference proceedings American Institute of Physics. Current Problems in Atmospheric Radiation (IRS 2008): Proceedings of the International Radiation Symposium (IRC/IAMAS). Foz do Iguaçu, Brazil, 3-8 August 2008, MELVILLE, NY: American Institute of Physics, vol. 1100, p. 331-334, doi:10.1063/1.3116984 Published 11 March 2009
  • A. Carissimo, G. Greco, G. Masiello, M. Matricardi, C. Serio Application of the σ-IASI radiative transfer model to IASI. In IRS 2008: Current Problems in Atmospheric Radiation. Proceedings of the International Radiation Symposium (IRC/IAMAS). Foz do Iguaçu, Brazil, 3-8 August 2008, MELVILLE, NY: American Institute of Physics, vol. 1100, p.31-34, doi:10.1063/1.3116981. Published: 11 March 2009
  • CARISSIMO A, GRIECO G, SERIO C, CUOMO V, MASIELLO G., SMITH W.L. Application of σ-IASI to NAST-I. In: IRS 2004: Current Problems in Atmospheric Radiation. Proceedings of the International Radiation Symposium. 23–28 August 2004. (vol. 148, pp. 247-250). ISBN/ISSN: 978-0-937194-48-5. HAMPTON, VIRGINIA: A. Deepak Publishing (UNITED STATES).Published: 01/01/2006
  • A.Carissimo, I. De Feis, C.Serio, The physical retrieval methodology for IASI: the δ-IASI code, Environmental Modelling & Software, Volume 20, Issue 9, Set 2005, Pag:1111-1126. doi:10.1016/j.envsoft.2004.07.003
  • SERIO C, CARISSIMO A, GRIECO G, MASIELLO G. (2005). Cloud Detection, Temperature and Water Vapor Retrieval from Hyperspectral Infrared Sounder Observations. In: Fourier Transform Spectroscopy/Hyperspectral Imaging and Sounding of the Environment Topical Meetings on CD-ROM. Alexandria, Virginia, USA, 31/01/2005 - 03/02/2005, WASHINGTON, DC: The Optical Society of America, HCM2, ISBN/ISSN: 1-55752-780-6
  • C. Serio, A.Carissimo, A. Lucchetta, G.Grieco, G. Masiello: AIDA phase III: Validation of the φ-IASI package with NAST-I data Final Report . EUMETSAT Technical Report (EUM/CO/02/1053/PS), EUMETSAT, Darmstadt, Germania
  • A.Carissimo, G.Grieco, C.Serio, I.De Feis, G.Masiello, Bias and Variance Properties of a new Inverse Tool for Geophysical Parameters. Proceeding of IEEE Gold Conference 2004.
  • A.Carissimo The Physical Inverse Model for IASI EUMETSAT Technical Report # 2, EUM/CO/02/1053/PS, EUMETSAT, Darmstadt, Germany.